Bioinformatics focuses on translational research that uses computational means to transform biological data into discoveries that help us better understand – and improve – life. It’s a discipline with such tremendous impact that further research exploration in the area is fully supported by the Indiana University Life Science Initiative, Indiana’s own Bioscience Initiative and INGEN (Indiana Genomics Initiative).
From the moment you enter our program, you will become fully immersed in ground-breaking research under the guidance of our world-renowned faculty. As part of course projects, independent research investigations and lab rotations, you’ll learn to use informatics, computer science, statistics, life sciences, molecular biology, genetics and a host of other disciplines to create and implement computational tools and applications that truly make a difference.
The Ph.D. in Informatics with Bioinformatics specialization is a 90-credit-hour program that integrates knowledge from informatics, computation, information systems, mathematics, biology and other related areas.
The program includes core courses, research rotations, your choice of minor, qualifying examinations and a dissertation.
Why study at SOIC?
- Renowned Faculty
Learn from approachable, internationally-respected faculty in personalized classes.
- Industry Connections
Our biopharmaceutical partners (Eli Lilly, Dow Agro and others) offer opportunities for internship, sponsorship and collaborative research.
- IUPUI’s Biomedical Research Campus
The IU School of Medicine, Regenstrief Institute, IU Simon Cancer Center and multiple research centers make IUPUI a leader in cross-disciplinary research.
Students must first apply and be accepted as a graduate student and meet the following prerequisites:
- Minimum of a Bachelor’s degree (with demonstrated technical skills)
- Minimum Overall GPA: 3.0 (4.0 point scale)
- Graduate Record Exam (GRE) scores from within the past five years.
Successful applicants to our master of science program must have a strong background in computing, information technology, and biology. You should be able to demonstrate the skills and knowledge required of the undergraduate Informatics degree.
Promising applicants lacking competencies necessary for admission may be allowed to take courses that will satisfy those requirements, as determined by School of Informatics and Computing faculty. Those courses, however, would not count towards degree or certificate completion.
Students holding a bachelor’s degree in computer science or a related field from an accredited four-year collegiate institution must have completed all or part of the prerequisite courses listed below:
- K322 Genetics and Molecular Biology and K324 Cell Biology or BIOL 507 Molecular Biology
Students holding a bachelor’s degree in life sciences or a related field from an accredited four-year collegiate institution must have completed all or part of the prerequisite courses listed below:
- Programming in C, C++, or Java (3 credits)
- Programming/Database (3 credits) (e.g. N510 Web-Database Concepts)
- Statistics (3 credits) (e.g. SPEA K300 or PSY B305)
Plan of Study
Students may test out of these.
For students with a biology background:
For students with a computing background:
- K322 Genetics and Molecular Biology and K324 Cell Biology or
- BIOL 507 Molecular Biology
Qualifying Courses (15 cr.)
- INFO B519 Introduction to Bioinformatics (3 cr.)
- INFO B529 Machine Learning in Bioinformatics (3 cr.)
- INFO I590 Statistical Methods in Bioinformatics (3 cr.)
- INFO B556 Biological Database Management (3 cr.)
- INFO I590 Computational Methods for Analyzing High-Throughput Data (3 cr.)
Required Core Courses (15 cr.)
- CSCI 59000 Algorithms in Bioinformatics (3 cr.)
- INFO I600 Professionalism and Pedagogy in Informatics (3 cr.)
- INFO B627 Advanced Seminar I – Bioinformatics (3 cr.)
- INFO B637 Advanced Seminar II – Bioinformatics (3 cr.)
- INFO I790 Independent Study/Rotation (3 cr.)
Elective Core Courses (15 cr.)
- INFO B619 Structural Bioinformatics (3 cr.)
- INFO B646 Computational System Biology (3 cr.)
- INFO B656 Translational Bioinformatics Applications (3 cr.)
- INFO I590 Computational Methods for Bioinformatics (3 cr.)
- INFO I590 Next Generation Genomic Data Analytics (3 cr.)
- MGEN G788/INFO I590 Next Generation Sequencing (3 cr.)
At most one of the following courses can be counted towards the elective core.
- INFO B535 Clinical Information Systems (3 cr.)
- INFO B642 Clinical Decision Support Systems (3 cr.)
- INFO I590 Analytics of Biomedical Data (3 cr.)
- INFO B512 Scientific Data Management (3 cr.)
- Other Health Informatics courses (advisor approval required)
Minor (minimum 12 cr.)
All students will be required to have an appropriate minor outside or partially inside the School of Informatics and Computing for a minimum 12.0 credit hours. Minors will be selected with the advisor’s recommendation. Some appropriate minors would include: biology, chemistry, cognitive psychology, computer science, information science, or statistics. In all cases the number of hours to be included in the minor will be consistent with the requirements of the unit granting the minor. Some of the courses included in the minor may also count toward the student’s methodology or other requirements.
No minimum or maximum credits
Students may take other electives (subject to approval) at the graduate level as needed for their specific research.
Qualifying Examination – Written
All students will take a written qualifying examination that covers the core courses (CORE A and B). The examination will be set by a group of faculty who are familiar with the content of the core courses. Examinations will be offered in August. Examinations must be completed by the beginning of the student’s fourth year in the program but can be completed before that time when the core courses are completed. Students who do not successfully complete the examination can retake the examination a second time.
Qualifying Examination – Oral
- The oral examination will take place after the student successfully passes the written exam. Students must pass both the written and oral exam before passing on to candidacy. Only two attempts to pass the oral examination will be allowed.
- The oral exam will be based on the student’s response to the written exam and any material from the core courses.
This is an oral review that covers in-depth knowledge of the student’s primary research area and dissertation proposal. The research proposal for dissertation must be approved by the student’s research committee. That committee may have the same membership as the program committee or the students may choose different members. The advisor for the dissertation will be a faculty member in the School of Informatics and Computing and a member of the Graduate Faculty. At least one the three members of the committee will be based outside of the school. The student will defend the thesis proposal at a public colloquium in the school. The review should be completed within one-year after passing the Qualifying Examinations.
Dissertation (30 cr. minimum)
Please refer to the IUPUI Graduate School Bulletin for more details on the dissertation process.